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In 1997, the FDA proposed to establish a dosing regimen, require warning statements, and affect other aspects of labeling for “dietary supplement” products containing ephedrine alkaloids. (Such products have been marketed for weight control, despite a lack of evidence that they are effective.)in July 1999, the U.S.
Besides Ephedra, there are many weight control ingredients that have been waiting in the wings. Some of these ingredients, common in dietary supplements, are becoming GRAS in functional foods. Others are food ingredients that have just become popular in the U.S. Still a few more are becoming more deeply rooted in the dietary supplement market–and new clinical evidence backs them up. The ingredients in this article have been classified according to different areas of nutrition: the lipids, the dietary fibers, the nutrients and the botanicals.
The Lipids
* CLA (Conjugated Linoleic Acid). The scientific evidence for CLA in weight loss was strong for laboratory animals (mice, pigs, rats, chicks), but controversial in humans. Recently, human clinical studies have started to change that.
CLA is an isomer of one of the two essential fatty acids, linoleic acid (the other being linolenic acid). Linoleic acid is first in the chain of the omega-6 fatty acids, and found mostly in vegetable products. However, CLA is frequently found in meat and dairy products naturally. CLA used in supplements most likely is manufactured from safflower oil. Common claims for CLA are that it builds muscle while reducing fat, induces thermogenesis, fights cancer, and is an antioxidant. Typical dosage recommendations are between 3-5mg daily.
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